Coombs Test

The Coombs test, also called direct antiglobulin test, is designed to detect immune-mediated erythrocyte destruction which occurs in autoimmune hemolytic anemias, and in some cases with infections and neoplastic disorders. Hemolysis in these diseases is caused by erythrocytes being coated with antibody (IgG, IgM) and/or complement components (C3). Coated erythrocytes are either lysed in the bloodstream or removed by phagocytes.

FPT

Failure of passive transfer (FPT) is the cause of most losses among newborn animals. Prevalence of FPT varies with the type of management and conditions. The key to diagnosis of FPT is a convenient field test, whether spot testing a commercial herd, or testing every newborn.